Mild hypothermia ameliorates ubiquitin synthesis and prevents delayed neuronal death in the gerbil hippocampus.
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چکیده
منابع مشابه
Mild hypothermia ameliorates ubiquitin synthesis and prevents delayed neuronal death in the gerbil hippocampus.
BACKGROUND AND PURPOSE The purpose of the present study is to determine the effect of mild hypothermia on the synthesis of ubiquitin, an important protein for maintenance of cell viability, in the hippocampal neurons following transient cerebral ischemia. METHODS Transient ischemia was induced by occluding both common carotid arteries for 5 minutes. In experiment 1, the animals were divided i...
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The implication of low affinity nerve growth factor receptor (p75NGFR), which is believed to play a pro-apoptotic role, in delayed neuronal death (DND) after ischemia in the gerbil hippocampus was investigated. Immunohistochemistry and Western blot analysis revealed that the presence of p75 NGFR immunoreactivity (IR) was negligible in the hippocampus of the sham control gerbil but appeared clea...
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ژورنال
عنوان ژورنال: Stroke
سال: 1991
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.22.12.1574